FEROPLAT. ANTITUMOR NANOCOMPOSITE – NEW FORM OF THE PREPARATION

PURPOSE:

To overcome drug resistance of anticancer drugs.

DESCRIPTION:

The antitumor ferromagnetic nanocomposite for overcoming drug resistance is capable of selective accumulation in the tumor focus and demonstrates sufficient antitumor activity against tumors with a drug resistance phenotype and has the same level of safety for healthy body tissues and official cytostatics. The use of modern nanotechnology has made it possible to create the Feroplat nanocomposite – a new dosage form based on a conjugated ferromagnet and cisplatin. The use of “Feroplat” and a static magnetic field leads to a selective increase in the concentration of cytostatics in the tumor.

ADVANTAGES:

There are no direct analogues of this development; comparison can only be made with platinum preparations. However, Feroplat has significant pharmacological advantages over the free form of cisplatin. It is capable of selective accumulation in the tumor focus, and therefore exhibits less systemic toxicity, the use of Feroplat allows, first of all, to reduce the nephrotoxicity of cisplatin. Unlike standard cisplatin chemotherapy, Feroplat is more active against cisplatin-resistant tumors. Unique technological properties, high innovative potential of a modern drug, combines successful technical solutions and pharmaceutical capabilities of the free preparation of cisplatin, which have been confirmed in an animal experiment – indicators of the pharmacokinetics of the nanocomposite, effective inhibition of tumor growth and reduction of the tumor node size. The results obtained and preclinical tests of the nanocomposite were carried out is a solid basis for the realization of the prospects for clinical trials and the further application of Feroplatu in clinical practice. The development solves a very urgent problem of oncology – overcoming drug resistance of anticancer drugs.

RECOMMENDED FIELD OF APPLICATION:

Medicine. Oncology clinics and patients with malignant neoplasms in whose therapy platinum preparations are used.

RESULTS OF THE RESEARCH:

Ready for implementation.

STAGE OF THE DEVELOPMENT READINESS:

Ready for implementation.

TRANSFER OPPORTUNITY:

• • • Joint bringing to the industrial level.
    • Creation of a joint venture.

NOVELTY:

1 patent of Ukraine.

If you are interested in this development, please fill out the form below

[wpforms id=”3826″]